Organisation:
Department:
Keywords:
Interests:
Diffusion tensor MRI · Dynamic susceptibility contrast perfusion MRI · Magnetization transfer MRI · Quantitative spin-lattice relaxation (T1) measurement · Application to normal ageing, brain tumours, schizophrenia, bipolar disorder, MND and MS.
Research Themes:
My primary research interest is in the development of MRI acquisition methods and post-processing techniques and their application to the study of the pathophysiology of diseases of the human brain.
Key Publications:
Bastin ME, Piatkowski JP, Storkey AJ, Brown LJ, MacLullich AM, Clayden JD. Tract Shape Modelling Provides Evidence of Topological Change in Corpus Callosum Genu During Normal Ageing. NeuroImage 2008;43(1):20-28.
Bastin ME, Clayden JD, Pattie A, Gerrish IF, Wardlaw JM, Deary IJ. Diffusion tensor and magnetization transfer MRI measurements of periventricular white matter hyperintensities in old age. Neurobiology of Aging 2009;30:125-136.
Bastin ME, Muñoz Maniega S, Ferguson KJ, Brown LJ, Wardlaw JM, MacLullich AM, Clayden JD. Quantifying the Effects of Normal Ageing on White Matter Structure using Unsupervised Tract Shape Modelling. NeuroImage 2010;51(1):1-10.
Collaborators:
Dr Sharon Abrahams, Psychology, University of Edinburgh Scotland
Dr Andrew McIntosh, Psychiatry, University of Edinburgh Scotland
Professor Joanna Wardlaw, Clinical Neurosciences, University of Edinburgh Scotland
Professor Douglas Steele, Medicine, Unversity of Dundee Scotland
Professor Keith Matthews, Medicine, University of Dundee Scotland
Professor Ian Deary, Psychology, University of Edinburgh Scotland