Organisation:
Department:
Interests:
Design and Synthesis of Molecular Imaging Agents for the Diagnosis and Treatment of Disease.
Research Themes:
Synthetic Chemistry, Transiton metal catalysed methodology, design of biologically active compounds, PET and SPECT imaging agents, fluorescent amino acids and peptides.
Key Publications:
A. A. Cant, R. Bhalla, S. L. Pimlott and A. Sutherland, Nickel-Catalysed Aromatic Finkelstein Reaction of Aryl and Heteroaryl Bromides, Chem. Commun., 2012, 48, 3993-3995.
S. L. Pimlott and A. Sutherland, Molecular Tracers for the PET and SPECT Imaging of Disease, Chem. Soc. Rev., 2011, 40, 149-162.
L. Stevenson, A. A. S. Tavares, A. Brunet, F. I. McGonagle, D. Dewar, S. L. Pimlott and A. Sutherland, New Iodinated Quinloine-2-Carboxamides for SPECT Imaging of the Translocator Protein, Bioorg. Med. Chem. Lett., 2010, 20, 954-957.
N. K. Jobson, A. R. Crawford, D. Dewar, S. L. Pimlott and A. Sutherland, Design and Synthesis of (2R,3S)-Iodoreboxetine Analogues for SPECT Imaging of the Noradrenaline Transporter, Bioorg. Med. Chem. Lett., 2009, 19, 4996-4998.
N. K. Jobson, R. Spike, A. R. Crawford, D. Dewar, S. L. Pimlott and A. Sutherland, Stereoselective Synthesis of (2S,3R)- and (2R,3S)-iodoreboxetine; Potential SPECT Imaging Agents for the Noradrenaline Transporter, Org. Biomol. Chem., 2008, 6, 2369-2376.
Collaborators:
Dr Sally Pimlott (University of Glasgow)
Professor Anthony Chalmers (University of Glasgow)
Dr Lutz Schweiger (University of Aberdeen)
Dr Gilles Tamagnan, Molecular NeuroImaging Ltd, USA
Dr Rajiv Bhalla, GE Healthcare, Medical Diagnostics International