This functional magnetic resonance imaging (fMRI) study examined changes in brain activation after prolonged (20 weeks) and stabilized treatment with the cholinesterase inhibitor galantamine in a small group of patients…
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…among 18 451 patients from the International Stroke Trial, first for all treatment groups combined. Then, among patients with AF, we examined the effects of treatment with subcutaneous UFH started…
The spatiotemporal evolution of stroke lesions, from acute injury to final tissue damage, is complex. Diffusion-weighted (DWI) and perfusion-weighted (PWI) imaging is commonly used to detect early ischemic changes and…
The use of curve-fitting and compartmental modelling for calculating physiological parameters from measured data has increased in popularity in recent years. Finding the ‘best fit’ of a model to data…
BACKGROUND: There is growing evidence that the gene catechol-O-methyltransferase (COMT) is involved in the etiopathogenesis of schizophrenia. This study sought to clarify the effects of the COMT Val158Met polymorphism on…
To identify common variants influencing body mass index (BMI), we analyzed genome-wide association data from 16,876 individuals of European descent. After previously reported variants in FTO, the strongest association signal…
Disfluencies can affect language comprehension, but to date, most studies have focused on disfluent pauses such as er. We investigated whether disfluent repetitions in speech have discernible effects on listeners…
The Institute of Physics (IOP) in Scotland, together with the SINAPSE, SUPA and SULSA research pools, is holding a competition asking post graduate students and early career researchers to send…
Reaction of the It-vinylidene complexes [Mo-2(eta(5)-C5H5)(2)(mu -SMe)(3)(mu-eta(1):eta(2)-C=CHR)](BF4) (1; R = Tol (1a), n-Pr (1b)) with NaBH4 produced the mu-alkylidyne derivatives [Mo-2(eta(5)-C5H5)(2)(mu-SMe)(3)(mu-SMe)(3)(mu-CCH2R)] (2; R = Tol (2a), n-Pr (2b)) in good…
…computed tomography in men and women. METHODS: COPDGene is a multicenter study of current and former smokers that underwent standardized volumetric chest computed tomography scans to assess airways, % emphysema,…
…and the accuracy and reproducibility of any computational segmentation technique. The most promising approach will need to combine various MR sequences and consider all these features for accurate EPVS determination….
BACKGROUND: Common carotid intima media thickness (CIMT) and ankle brachial pressure index (ABPI) are used as surrogate marker of atherosclerosis, and have been shown to correlate with arterial stiffness, however…
OBJECTIVE: Echocardiography is widely used in the investigation of patients with suspected SSc-associated pulmonary arterial hypertension (SSc-PAH). We investigated whether CT pulmonary angiography (CTPA) provides additive diagnostic value. METHODS: Data…
BACKGROUND: Depressive symptoms are prominent psychopathological features of Huntington’s disease (HD), making a negative impact on social functioning and well-being. METHOD: We compared the frequencies of a history of depression,…
…Cox MVA p=0.040). Conclusions: Molecular biomarkers (Leptin in particular) combine with FDG PET to optimise response prediction in EGJAc. Further investigation of this combined molecular and imaging approach is warranted….