…29 females) representative older adults aged 71.1-74.3 years from a community-dwelling ageing cohort, the Lothian Birth Cohort 1936. A semi-automatically derived current ICV measurement obtained from high resolution T1-weighted volume…
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…form 5′-fluoro-5′-deoxyadenosine (5′-FDA) and L-methionine. To obtain an insight into the mechanism of this unusual enzymatic reaction and to elucidate the role of the enzyme in catalysis, we have explored…
…interview in a Neurovascular Genetics clinic (182 first-degree and 242 second-degree relatives identified). Family history obtained from structured interview was compared to family history initially documented at presentation. At initial…
…relative conversions of ortho-, meta- and para-fluorolittorine analogues were used to obtain information on the likely intermediacy of either a benzylic radical or benzylic carbocation intermediate. The data suggest that…
…of the index finger. The results ale presented for five different angles of joint flexion for a single subject. The moment arm data obtained differ from previous studies, where results…
…be obtained under nonevaluative encoding conditions, such as when object ownership is used to evoke self-reference. Using fMRI, the current study explored the neural correlates of object ownership. During scanning,…
…angiograms obtained at the time of first-ever AVM diagnosis. The allocation of the films to observers was balanced for AVM size and complexity. Every observer was compared with himself and…
…of 4-fluoro-pyrans and -piperidines were investigated. The products were obtained in good yields, but only with moderate diastereoselectivity. These Prins fluorination reactions can be accelerated under microwave conditions. The study…
There is increasing interest in obtaining quantitative imaging parameters to aid in the assessment of tumor responses to treatment. In this study, the feasibility of performing integrated diffusion, perfusion and…
In this paper we present the radiochemical synthesis of the novel compound [N-methyl-C-11]methylene blue. The synthesis of [N-methyl-C-11]methylene blue was accomplished by means of C-11-methylation of commercially available Azure B…
Background: Ischemic stroke is the leading cause of mortality worldwide and a major contributor to neurological disability and dementia. Terutroban is a specific TP receptor antagonist with antithrombotic, antivasoconstrictive, and…
…Efforts are being made to diagnose these neurodegenerative disorders in the early stages. Indeed, early diagnosis helps patients to obtain the maximum treatment benefit before significant mental decline occurs. The…
[GRAPHICS] On treatment with samarium(II) iodide, gamma,delta-unsaturated ketones undergo very different processes depending upon the nature of the reaction conditions. Employing samarium(II) iodide and MeOH, functionalized syn-cyclopentanol products are obtained…
…enhance the sensitivity of perfusion-based fMRI experiments. To investigate whether a comparable effect was detectable in awake normal humans, changes in cerebral blood flow (Delta CBF) and the effective transverse…
…harmful recombination. We obtain simple approximations for the limits of tight linkage, and strong assortment, and show how assortment alleles can invade through associations with other components of reproductive isolation….