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Is inadequate family history a barrier to diagnosis in CADASIL?

…interview in a Neurovascular Genetics clinic (182 first-degree and 242 second-degree relatives identified). Family history obtained from structured interview was compared to family history initially documented at presentation. At initial…

Mine and me: exploring the neural basis of object ownership

…be obtained under nonevaluative encoding conditions, such as when object ownership is used to evoke self-reference. Using fMRI, the current study explored the neural correlates of object ownership. During scanning,…

Radiosynthesis of [N-methyl-C-11]methylene blue

In this paper we present the radiochemical synthesis of the novel compound [N-methyl-C-11]methylene blue. The synthesis of [N-methyl-C-11]methylene blue was accomplished by means of C-11-methylation of commercially available Azure B…

Rationale and Design of a Randomized, Double-Blind, Parallel-Group Study of Terutroban 30 mg/day versus Aspirin 100 mg/day in Stroke Patients: The Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin with Terutroban in Patients with a History of Ischemic Stroke or Transient Ischemic Attack (PERFORM) Study

Background: Ischemic stroke is the leading cause of mortality worldwide and a major contributor to neurological disability and dementia. Terutroban is a specific TP receptor antagonist with antithrombotic, antivasoconstrictive, and…

THE EVOLUTION OF STRONG REPRODUCTIVE ISOLATION

…harmful recombination. We obtain simple approximations for the limits of tight linkage, and strong assortment, and show how assortment alleles can invade through associations with other components of reproductive isolation….

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