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Rationale and Design of a Randomized, Double-Blind, Parallel-Group Study of Terutroban 30 mg/day versus Aspirin 100 mg/day in Stroke Patients: The Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin with Terutroban in Patients with a History of Ischemic Stroke or Transient Ischemic Attack (PERFORM) Study

Background: Ischemic stroke is the leading cause of mortality worldwide and a major contributor to neurological disability and dementia. Terutroban is a specific TP receptor antagonist with antithrombotic, antivasoconstrictive, and…

Spatial normalization of lesioned HMPAO-SPECT images

…order to obtain images with controllable characteristics. We examined the use of basis functions (in SPM96 and SPM99) and other nonlinear models (in AIR3.08) designed to achieve optimum alignment between…

THE EVOLUTION OF STRONG REPRODUCTIVE ISOLATION

…harmful recombination. We obtain simple approximations for the limits of tight linkage, and strong assortment, and show how assortment alleles can invade through associations with other components of reproductive isolation….

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