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NXY-059 for acute ischemic stroke

…modified Rankin scale, as compared with placebo (P=0.038 by the Cochran-Mantel-Haenszel test). The common odds ratio for improvement across all categories of the scale was 1.20 (95 percent confidence interval,…

Activation and functionalization of vinylic C-F bonds by transition metal compounds: The factors determining reactions between nucleophiles and a (perfluorovinyl)diiron(I) complex; Syntheses of diiron derivatives containing new C-N, C-S, C-H and C-O bonds

…to Pearson, produces alpha, beta-substituted thiaferracyclopentadiene [(Fe(CO)(3)}(2) t-S(Me)C(CF3)CO(NHR)Cbeta(NHR)C-alpha [R = Ph (5a), NHC(O)OMe (5b)] complexes. It is suggested that these compounds form through initial nucleophilic attack at C. to give…

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