Keywords:
Interests:
I am acutely aware of the cost and complexity of advanced clinical imaging technologies and am keen to bring together professionals from all sectors – health care, academia and industry – to address the challenges of using human imaging to advance our knowledge of health and disease. I have a particular interest in working with colleagues exploring the biological basis of neurological and mental health conditions. As a clinical physicist I have a focus on commercialisation of technologies developed by identifying opportunities arising from every day clinical practice. I am also an enthusiastic participant in the training and mentoring of young scientists and technologists.
Research Themes:
Application of novel tracers in molecular imaging, Application of novel techniques in MRI, Development of medical devices
Key Publications:
Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study.
Cavanagh J, Paterson C, McLean J, Pimlott S, McDonald M, Patterson J, Wyper D, McInnes I.
Ann Rheum Dis. 2010 Jun;69(6):1251-2. doi: 10.1136/ard.2009.107912.
SSRI antidepressants do not confound single photon emission computed tomography (SPECT) imaging studies using the alpha4beta2 nicotinic acetylcholine receptor [123I]5-I-A85380 ligand: in vivo and in vitro evidence.
Cavanagh J, Patterson J, Pimlott S, Wyper D, Dewar D.
Synapse. 2010 Feb;64(2):111-6.
In vivo [(123)I]CNS-1261 binding to D-serine-activated and MK801-blocked NMDA receptors: A storage phosphor imaging study in rats.
Knol RJ, de Bruin K, van Eck-Smit BL, Pimlott S, Wyper DJ, Booij J.
Synapse. 2009 Jul;63(7):557-64.
Alterations in nicotinic α4β2 receptor binding in vascular dementia using ¹²³I-5IA-85380 SPECT: comparison with regional cerebral blood flow.
Colloby SJ, Firbank MJ, Pakrasi S, Perry EK, Pimlott SL, Wyper DJ, McKeith IG, Williams ED, O’Brien JT.
Neurobiol Aging. 2011 Feb;32(2):293-301.
Localisation of regions of intense pleasure response evoked by soccer goals.
McLean J, Brennan D, Wyper D, Condon B, Hadley D, Cavanagh J.
Psychiatry Res. 2009 Jan 30;171(1):33-43.
Collaborators:
SINAPSE colleagues
Gilles Tamagnan USA
Dino Jaroszynski, Strathclyde